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11.31 (Campbell1958), which illustrates the dynamic relation-ship between pleural pressure and lung volume.Since pleural pressure is dif?cult to measure,the surrogate measurement of esophageal pres-sure is commonly utilized for both research andclinical applications of WOB measurement.Esophageal pressure swings during inspirationneed to overcome two forces: the elastic forcesof the lung parenchyma and chest wall and theresistive forces generated by the movementof gas through the airways.

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